Estrogen and breast cancer: can less mean more?

نویسندگان

  • Marc D Bullock
  • Andreia M Silva
  • George A Calin
چکیده

Estrogen and Breast Cancer: can less mean more? Marc D Bullock, Andreia M Silva & George A Calin a Cancer Sciences Unit; University of Southampton School of Medicine; Southampton, UK b Division of Surgery; University Hospital Southampton; Southampton, UK c Department of Experimental Therapeutics; The University of Texas MD Anderson Cancer Center; Houston, TX USA d Instituto de Investigação em Saúde; Universidade do Porto; Porto, Portugal e Institute of Biomedical Engineering; Universidade do Porto; Porto, Portugal f Center for RNA Interference and Non-Coding RNAs; The University of Texas MD Anderson Cancer Center; Houston, TX USA Accepted author version posted online: 19 Jun 2015.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Bioinformatics-Based Prediction of FUT8 as a Therapeutic Target in Estrogen Receptor-Positive Breast Cancer

Abstract Introduction: Estrogen receptor-positive (ER-positive) breast cancer is a subgroup of breast tumors that is more likely to respond to hormone therapy. ER-positive and ER- negative breast cancers tend to show different patterns of metastasis because of different signaling cascade and genes that are activated by estrogen response. Genetic factors can contribute to high rates of metastas...

متن کامل

Bioinformatics-Based Prediction of FUT8 as a Therapeutic Target in Estrogen Receptor-Positive Breast Cancer

Abstract Introduction: Estrogen receptor-positive (ER-positive) breast cancer is a subgroup of breast tumors that is more likely to respond to hormone therapy. ER-positive and ER- negative breast cancers tend to show different patterns of metastasis because of different signaling cascade and genes that are activated by estrogen response. Genetic factors can contribute to high rates of metastas...

متن کامل

The hormonal milieu in primary breast cancer: A correlation between steroid receptors and serum estradiol, progesterone and prolactin

Background: The female breast is subjected to a lifetime of hormonal controls, whose effect is evident at the time of menarche and during the menstrual cycle, pregnancy and lactation. Studies have reported multiple risk factors for breast cancer, some of which are a reflection of hormonally mediated events. The steroid receptors are also served as prognostic factors for evaluating status of mal...

متن کامل

Phytoestrogens: recent developments

Phytoestrogens are polyphenolic non-steroidal plant compounds with estrogen like activity exerted through estrogen receptors. These receptors are distributed in several tissues such as male and female reproductive systems, bones, cardiovascular and central nervous systems. These natural phenolic compounds include isoflavonoids, flavonoids, lignans and stilbenes. Isoflavonoids are the most studi...

متن کامل

Phytoestrogens: recent developments

Phytoestrogens are polyphenolic non-steroidal plant compounds with estrogen like activity exerted through estrogen receptors. These receptors are distributed in several tissues such as male and female reproductive systems, bones, cardiovascular and central nervous systems. These natural phenolic compounds include isoflavonoids, flavonoids, lignans and stilbenes. Isoflavonoids are the most studi...

متن کامل

Onm-4: Reproductive Factors and Breast Cancer Incidence in Premenopousal Patients: A Case-Control Study

Background: Menstrual characteristics may serve as surrogate measures of endogenous estrogen and may be related to breast cancer risk. This case-control study investigated the relationship between menstrual factors and risk of breast cancer incidence in Iranian Center for Breast Cancer (ICBC). Materials and Methods: Forty seven Cases of breast cancer referred to ICBC and 77 controls were studie...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Cell cycle

دوره 14 14  شماره 

صفحات  -

تاریخ انتشار 2015